Wang Lab

Research Areas

Neurodegenerative Diseases

Investigating molecular mechanisms and novel biomarkers of Alzheimer's Disease and other neurodegenerative disorders:

Epigenetic modifications in early synaptic dysfunction of AD
Post-translational modifications in early synaptic dysfunction of AD
Biomarker discovery and validation

Cancer Bioinformatics

Multi-omics data integration and bioinformatics tool development for pan-cancer research:

Pan-cancer analysis and integrative omics
Tumor immune microenvironment
Bioinformatics tool development (CancerOmicsStudio, TCGAplot)

Publications

1. Yu L*, Liu W*, Liao C, Shen N, Liu A#, Cheng L#, Wang X#. The interaction between circadian syndrome and genetic susceptibility in the risk of incident dementia. J Prev Alzheimers Dis. 2025 May;12(5):100089.

2. Tan L*, Xie J*, Liao C*, Li X, Zhang W, Cai C#, Cheng L#, Wang X#. Tetrahedral framework nucleic acids inhibit Aβ-mediated ferroptosis and ameliorate cognitive and synaptic impairments in Alzheimer's disease. J Nanobiotechnology. 2024 Nov 7;22(1):682.

3. Liao C, Wang X. TCGAplot: an R package for integrative pan-cancer analysis. BMC Bioinformatics. 2023 Dec 17;24(1):483.

4. Wang X*#, Xie J*, Tan L*, Lu Y, Shen N, Li J, Hu H, Li H, Li X#, Cheng L#. N6-methyladenosine-modified circRIMS2 mediates synaptic and memory impairments by activating GluN2B ubiquitination in Alzheimer's disease. Transl Neurodegener. 2023 Nov 28;12(1):53.

View All Publications on PubMed

NSFC Grants

Grant No.: 82572661 | 2026.01-2029.12 | Active
Grant No.: 82372337 | 2024.01-2027.12 | Active
Grant No.: 81500925 | 2016.01-2018.12 | Completed

Online Tools

CancerOmicsStudio - Integrative multi-omics cancer analysis with drug, CRISPR, and single-cell modules
TCGAplot - an R package for integrative pan-cancer analysis and visualization of TCGA multi-omics data

Current Members

Master student

Chenqi Liao

Danyang Sun